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Article

Targeting BRAF aberrations in advanced colorectal carcinoma: from bench to bedside.

Future oncology (London, England) - 1 Jan 2016

Abdel-Rahman Omar

Abstract excerpt

Colorectal cancer (CRC) is a global health problem with profound mortality and morbidity effects particularly in the advanced/metastatic setting. Because of the recent understanding of the biology of this disease, many candidate targets have come into light for therapeutic evaluation. The current review is about evaluating the preclinical and clinical aspects of BRAF as a therapeutic target in this disease. The...

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Source

Identifiers

PMID: 26616508
DOI: 10.2217/fon.15.226

Genes

BRAF
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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