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Treatment of Advanced BRAF-Mutated Colorectal Cancer: Where We Are and Where We Are Going.

Clinical colorectal cancer - 1 Jun 2022

Sun Chen, España Sofia, Buges Cristina, Layos Laura, Hierro Cinta, Manzano Jose Luis

Abstract excerpt

In recent years, studies on the molecular typing of colorectal cancer have matured, and the V-raf murine sarcoma viral oncogene homolog B (BRAF) of the mitogen-activated protein kinase pathway has been shown to be an important effector molecule of this pathway and regulates the occurrence and development of colorectal cancer. Clinical observations indicate that colorectal cancer patients harboring the BRAF V600E...

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PMID: 35277355
DOI: 10.1016/j.clcc.2022.01.009

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