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Article

Age-Related Macular Degeneration and Extramacular Drusen: Genetic Associations in the Coimbra Eye Study.

Investigative ophthalmology & visual science - 1 May 2024

Farinha Cláudia, Barreto Patrícia, Coimbra Rita, Machado Maria Beatriz, Figueiredo Inês, Cachulo Maria Luz, Cunha-Vaz José, Silva Rufino

Abstract excerpt

Purpose: To explore the association between the genetics of age-related macular degeneration (AMD) and extramacular drusen (EMD) in patients with and without AMD. Methods: We included 1753 eyes (912 subjects) with phenotypic characterization regarding AMD and EMD. Genetic sequencing and the genetic risk score (GRS) for AMD were performed according to the EYE-RISK consortium methodology. To test for differences in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38776116
DOI: 10.1167/iovs.65.5.35
PMCID: PMC11127495

Genes

EMD
ARMS2
C3
CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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