Article
On the Causes of Evolutionary Transition:Transversion Bias.
Molecular biology and evolution - 1 Mar 2016
Stoltzfus Arlin, Norris Ryan W
Abstract excerpt
A pattern in which nucleotide transitions are favored several fold over transversions is common in molecular evolution. When this pattern occurs among amino acid replacements, explanations often invoke an effect of selection, on the grounds that transitions are more conservative in their effects on proteins. However, the underlying hypothesis of conservative transitions has never been tested directly. Here we...
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