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Article

Novel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, Obtained by Genetic Reversion Screens.

PloS one - 1 Jan 2015

Lambie Eric J, Bruce Robert D, Zielich Jeffrey, Yuen Sonia N

Abstract excerpt

TRP (Transient Receptor Potential) cation channels of the TRPM subfamily have been found to be critically important for the regulation of Mg2+ homeostasis in both protostomes (e.g., the nematode, C. elegans, and the insect, D. melanogaster) and deuterostomes (e.g., humans). Although significant progress has been made toward understanding how the activities of these channels are regulated, there are still major...

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Source

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Identifiers

PMID: 26606136
DOI: 10.1371/journal.pone.0143445
PMCID: PMC4659536

Genes

TRPM7
TRPM6
TRPM1

Provenance

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Related research

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Novel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, Obtained by Genetic Reversion Screens.PMID 26606136Read ↗

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