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Article

Magnesium excretion in C. elegans requires the activity of the GTL-2 TRPM channel.

PloS one - 8 Mar 2010

Teramoto Takayuki, Sternick Laura A, Kage-Nakadai Eriko, Sajjadi Shirine, Siembida Jakub, Mitani Shohei, Iwasaki Kouichi, Lambie Eric J

Abstract excerpt

Systemic magnesium homeostasis in mammals is primarily governed by the activities of the TRPM6 and TRPM7 cation channels, which mediate both uptake by the intestinal epithelial cells and reabsorption by the distal convoluted tubule cells in the kidney. In the nematode, C. elegans, intestinal magnesium uptake is dependent on the activities of the TRPM channel proteins, GON-2 and GTL-1. In this paper we provide...

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Source

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Identifiers

PMID: 20221407
DOI: 10.1371/journal.pone.0009589
PMCID: PMC2833210

Genes

TRPM6
TRPM7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Magnesium excretion in C. elegans requires the activity of the GTL-2 TRPM channel.PMID 20221407Read ↗

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