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Article

Are lung cysts in renal cell cancer (RCC) patients an indication for FLCN mutation analysis?

Familial cancer - 1 Apr 2016

Johannesma Paul C, Houweling Arjan C, Menko Fred H, van de Beek I, Reinhard Rinze, Gille Johan J P, van Waesberghe JanHein T M, Thunnissen Erik, Starink Theo M, Postmus Pieter E, van Moorselaar R Jeroen A

Abstract excerpt

Renal cell cancer (RCC) represents 2-3% of all cancers and is the most lethal of the urologic malignancies, in a minority of cases caused by a genetic predisposition. Birt-Hogg-Dubé syndrome (BHD) is one of the hereditary renal cancer syndromes. As the histological subtype and clinical presentation in BHD are highly variable, this syndrome is easily missed. Lung cysts--mainly under the main carina--are reported...

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Source

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Identifiers

PMID: 26603437
DOI: 10.1007/s10689-015-9853-5
PMCID: PMC4803815

Genes

FLCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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