Article
Renal cancer and pneumothorax risk in Birt-Hogg-Dubé syndrome; an analysis of 115 FLCN mutation carriers from 35 BHD families.
British journal of cancer - 6 Dec 2011
Houweling A C, Gijezen L M, Jonker M A, van Doorn M B A, Oldenburg R A, van Spaendonck-Zwarts K Y, Leter E M, van Os T A, van Grieken N C T, Jaspars E H, de Jong M M, Bongers E M H F, Johannesma P C, Postmus P E, van Moorselaar R J A, van Waesberghe J-Htm, Starink T M, van Steensel M A M, Gille J J P, Menko F H
Abstract excerpt
BACKGROUND: Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant condition caused by germline FLCN mutations, and characterised by fibrofolliculomas, pneumothorax and renal cancer. The renal cancer risk, cancer phenotype and pneumothorax risk of BHD have not yet been fully clarified. The main focus of this study was to assess the risk of renal cancer, the histological subtypes of renal tumours and the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.