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Article

Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate.

Molecular psychiatry - 1 Oct 2016

Mastronardi C A, Pillai E, Pineda D A, Martinez A F, Lopera F, Velez J I, Palacio J D, Patel H, Easteal S, Acosta M T, Castellanos F X, Muenke M, Arcos-Burgos M

Abstract excerpt

Attention-deficit/hyperactivity disorder (ADHD) is a heritable, chronic, neurodevelopmental disorder with serious long-term repercussions. Despite being one of the most common cognitive disorders, the clinical diagnosis of ADHD is based on subjective assessments of perceived behaviors. Endophenotypes (neurobiological markers that cosegregate and are associated with an illness) are thought to provide a more...

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Identifiers

PMID: 26598068
DOI: 10.1038/mp.2015.172
PMCID: PMC4879118

Genes

CHRNA4
FGF1
POLR2A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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