Article
Validation and extension of the endophenotype model in ADHD patterns of inheritance in a family study of inhibitory control.
The American journal of psychiatry - 1 Jun 2009
Goos Lisa M, Crosbie Jennifer, Payne Shalaine, Schachar Russell
Abstract excerpt
OBJECTIVE: Endophenotypes, markers of underlying liability to psychiatric disorders, can improve the power to detect genetic risks relative to a complex clinical endpoint. Motor response inhibition is a prime candidate endophenotype in ADHD. In this study, the authors sought to extend the endophenotype model and further demonstrate its utility by investigating the parental origin of shared genetic risk in ADHD....
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