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Article

The PEX1 ATPase Stabilizes PEX6 and Plays Essential Roles in Peroxisome Biology.

Plant physiology - 1 Aug 2017

Rinaldi Mauro A, Fleming Wendell A, Gonzalez Kim L, Park Jaeseok, Ventura Meredith J, Patel Ashish B, Bartel Bonnie

Abstract excerpt

A variety of metabolic pathways are sequestered in peroxisomes, conserved organelles that are essential for human and plant survival. Peroxin (PEX) proteins generate and maintain peroxisomes. The PEX1 ATPase facilitates recycling of the peroxisome matrix protein receptor PEX5 and is the most commonly affected peroxin in human peroxisome biogenesis disorders. Here, we describe the isolation and characterization...

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Source

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Identifiers

PMID: 28600347
DOI: 10.1104/pp.17.00548
PMCID: PMC5543962

Genes

PEX1
PEX6
PEX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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The PEX1 ATPase Stabilizes PEX6 and Plays Essential Roles in Peroxisome Biology.PMID 28600347Read ↗

A pex1 missense mutation improves peroxisome function in a subset of Arabidopsis pex6 mutants without restoring PEX5 recyclingSemantic proximity Read ↗

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The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders.Semantic proximity Read ↗

The Arabidopsis PEX12 gene is required for peroxisome biogenesis and is essential for development.Semantic proximity Read ↗

A subtle interplay between three Pex11 proteins shapes de novo formation and fission of peroxisomes.Semantic proximity Read ↗

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