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Article

Human Polymorphisms in Placentally Expressed Genes and Their Association With Susceptibility to Congenital Trypanosoma cruzi Infection.

The Journal of infectious diseases - 15 Apr 2016

Juiz Natalia A, Cayo Nelly M, Burgos Marianela, Salvo Miriam E, Nasser Julio R, Búa Jacqueline, Longhi Silvia A, Schijman Alejandro G

Abstract excerpt

BACKGROUND: It is currently unclear why only a proportion of children born to Trypanosoma cruzi-infected mothers acquire the infection. We have examined the association of 11 single-nucleotide polymorphisms (SNPs) located in genes coding for placental expression enzymes as genetic markers of susceptibility to congenital T. cruzi infection (hereafter, "congenital infection"): rs2014683 and rs1048988 in ALPP;...

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Source

Identifiers

PMID: 26597259
DOI: 10.1093/infdis/jiv561

Genes

ADAM12
MMP2
ALPP
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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