Article
Classification of Parkinson's Disease Genotypes in Drosophila Using Spatiotemporal Profiling of Vision.
Scientific reports - 24 Nov 2015
West Ryan J H, Elliott Christopher J H, Wade Alex R
Abstract excerpt
Electrophysiological studies indicate altered contrast processing in some Parkinson's Disease (PD) patients. We recently demonstrated that vision is altered in Drosophila PD models and hypothesised that different types of genetic and idiopathic PD may affect dopaminergic visual signalling pathways differently. Here we asked whether visual responses in Drosophila could be used to identify PD mutations. To mimic a...
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