Article
Identification and Characterization of Lineage(-)CD45(-)Sca-1(+) VSEL Phenotypic Cells Residing in Adult Mouse Bone Tissue.
Stem cells and development - 1 Jan 2016
Nakatsuka Ryusuke, Iwaki Ryuji, Matsuoka Yoshikazu, Sumide Keisuke, Kawamura Hiroshi, Fujioka Tatsuya, Sasaki Yutaka, Uemura Yasushi, Asano Hiroaki, Kwon A-Hon, Sonoda Yoshiaki
Abstract excerpt
Murine bone marrow (BM)-derived very small embryonic-like stem cells (BM VSELs), defined by a lineage-negative (Lin(-)), CD45-negative (CD45(-)), Sca-1-positive (Sca-1(+)) immunophenotype, were previously reported as postnatal pluripotent stem cells (SCs). We developed a highly efficient method for isolating Lin(-)CD45(-)Sca-1(+) small cells using enzymatic treatment of murine bone. We designated these cells as...
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