Article
Murine bone marrow Lin⁻Sca⁻1⁺CD45⁻ very small embryonic-like (VSEL) cells are heterogeneous population lacking Oct-4A expression.
PloS one - 1 Jan 2013
Szade Krzysztof, Bukowska-Strakova Karolina, Nowak Witold Norbert, Szade Agata, Kachamakova-Trojanowska Neli, Zukowska Monika, Jozkowicz Alicja, Dulak Jozef
Abstract excerpt
Murine very small embryonic-like (VSEL) cells, defined by the Lin(-)Sca-1(+)CD45(-) phenotype and small size, were described as pluripotent cells and proposed to be the most primitive hematopoietic precursors in adult bone marrow. Although their isolation and potential application rely entirely on flow cytometry, the immunophenotype of VSELs has not been extensively characterized. Our aim was to analyze the...
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