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Bone marrow‐derived very small embryonic‐like stem cells: Their developmental origin and biological significance

11 May 2007

Abstract excerpt

Data from our and other laboratories provide evidence that bone marrow (BM) contains a population of stem cells that expresses early developmental markers such as (1) stage-specific embryonic antigen (SSEA) and (2) transcription factors Oct-4 and Nanog. These are the markers characteristic for embryonic stem cells, epiblast stem cells, and primordial germ cells (PGC). The presence of these stem cells in adult BM...

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PMID: 17497671
DOI: 10.1002/dvdy.21180

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