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Article

Heme A synthase in bacteria depends on one pair of cysteinyls for activity.

Biochimica et biophysica acta - 1 Feb 2016

Lewin Anna, Hederstedt Lars

Abstract excerpt

Heme A is a prosthetic group unique for cytochrome a-type respiratory oxidases in mammals, plants and many microorganisms. The poorly understood integral membrane protein heme A synthase catalyzes the synthesis of heme A from heme O. In bacteria, but not in mitochondria, this enzyme contains one or two pairs of cysteine residues that are present in predicted hydrophilic polypeptide loops on the extracytoplasmic...

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PMID: 26592143
DOI: 10.1016/j.bbabio.2015.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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