Article
Bacillus subtilis ResA is a thiol-disulfide oxidoreductase involved in cytochrome c synthesis.
The Journal of biological chemistry - 16 May 2003
Erlendsson Lýğur S, Acheson Richard M, Hederstedt Lars, Le Brun Nick E
Abstract excerpt
Covalent attachment of heme to apocytochromes c in bacteria occurs on the outside of the cytoplasmic membrane and requires two reduced cysteinyls at the heme binding site. A constructed ResA-deficient Bacillus subtilis strain was found to lack c-type cytochromes. Cytochrome c synthesis was restored in the mutant by: (i) in trans expression of resA; (ii) deficiency in BdbD, a thiol-disulfide oxidoreductase that...
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