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Article

A Y-linked anti-Müllerian hormone duplication takes over a critical role in sex determination.

Proceedings of the National Academy of Sciences of the United States of America - 21 Feb 2012

Hattori Ricardo S, Murai Yu, Oura Miho, Masuda Shuji, Majhi Sullip K, Sakamoto Takashi, Fernandino Juan I, Somoza Gustavo M, Yokota Masashi, Strüssmann Carlos A

Abstract excerpt

Gonadal sex determination in vertebrates generally follows a sequence of genetically programmed events. In what is seemingly becoming a pattern, all confirmed or current candidate "master" sex-determining genes reported in this group, e.g., SRY in eutherian mammals, DMY/dmrt1bY in medaka, DM-W in the African clawed frog, and DMRT1 in chicken encode transcription factors. In contrast, here we show that a...

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Source

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Identifiers

PMID: 22323585
DOI: 10.1073/pnas.1018392109
PMCID: PMC3286941

Genes

DMRT1
SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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