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Article

An accelerated senescence response to radiation in wild-type p53 glioblastoma multiforme cells

1 Jul 2006

Abstract excerpt

OBJECT: Radiotherapy is one of the few treatment options available for glioblastoma multiforme (GBM); however, the basis for its overall ineffectiveness in GBM is not fully understood. The present study was designed to explore the nature of the response to ionizing radiation in GBM cells to gain insight into the basis for the general failure of radiotherapy in the treatment of this disease. METHODS: The response...

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PMID: 16871885
DOI: 10.3171/jns.2006.105.1.111

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