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Extensive molecular genetic survey of Taiwanese patients with amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Oct 2014

Soong Bing-Wen, Lin Kon-Ping, Guo Yuh-Cherng, Lin Chou-Ching K, Tsai Pei-Chien, Liao Yi-Chu, Lu Yi-Chun, Wang Shuu-Jiun, Tsai Ching-Piao, Lee Yi-Chung

Abstract excerpt

Identification of genetic mutations has been of burgeoning importance in amyotrophic lateral sclerosis (ALS) in recent years. The aim of this study was to determine the frequency and spectrum of mutations in major ALS-causing genes in a Taiwanese ALS cohort of Han Chinese origin. Mutational analyses of the SOD1, TARDBP, FUS, OPTN, VCP, UBQLN2, SQSTM1, PFN1, HNRNPA1, and HNRNPA2B1 genes were carried out by direct...

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Amyotrophic Lateral Sclerosis
Ataxins
C9orf72 Protein
DNA Repeat Expansion
Superoxide Dismutase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Superoxide Dismutase-1

Transcription Factor TFIIIA

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Identifiers

PMID: 24908169
DOI: 10.1016/j.neurobiolaging.2014.05.008

Genes

SOD1
OPTN
ATXN2
FUS
HNRNPA1
PFN1
SQSTM1
TARDBP
UBQLN2
VCP

Variants

Provenance

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