Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins

Abstract excerpt

Macrophages are innate immune cells of dynamic phenotype that rapidly respond to external stimuli in the microenvironment by altering their phenotype to respond to and to direct the immune response. The ability to dynamically change phenotype must be carefully regulated to prevent uncontrolled inflammatory responses and subsequently to promote resolution of inflammation. The suppressor of cytokine signaling...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chemokine receptors and signaling
• Share to Cytokine Signaling Pathways and Interactions
• Share to Immune cells in cancer