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Article

Clinico-pathological nomogram for predicting BRAF mutational status of metastatic colorectal cancer.

British journal of cancer - 12 Jan 2016

Loupakis Fotios, Moretto Roberto, Aprile Giuseppe, Muntoni Marta, Cremolini Chiara, Iacono Donatella, Casagrande Mariaelena, Ferrari Laura, Salvatore Lisa, Schirripa Marta, Rossini Daniele, De Maglio Giovanna, Fasola Gianpiero, Calvetti Lorenzo, Pilotto Sara, Carbognin Luisa, Fontanini Gabriella, Tortora Giampaolo, Falcone Alfredo, Sperduti Isabella, Bria Emilio

Abstract excerpt

BACKGROUND: In metastatic colorectal cancer (mCRC), BRAFV600E mutation has been variously associated to specific clinico-pathological features. METHODS: Two large retrospective series of mCRC patients from two Italian Institutions were used as training-set (TS) and validation-set (VS) for developing a nomogram predictive of BRAFV600E status. The model was internally and externally validated. RESULTS: In the TS,...

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Identifiers

PMID: 26575603
DOI: 10.1038/bjc.2015.399
PMCID: PMC4716533

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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