Article
Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection.
The New England journal of medicine - 31 Dec 2015
Feld Jordan J, Jacobson Ira M, Hézode Christophe, Asselah Tarik, Ruane Peter J, Gruener Norbert, Abergel Armand, Mangia Alessandra, Lai Ching-Lung, Chan Henry L Y, Mazzotta Francesco, Moreno Christophe, Yoshida Eric, Shafran Stephen D, Towner William J, Tran Tram T, McNally John, Osinusi Anu, Svarovskaia Evguenia, Zhu Yanni, Brainard Diana M, McHutchison John G, Agarwal Kosh, Zeuzem Stefan
Abstract excerpt
BACKGROUND: A simple treatment regimen that is effective in a broad range of patients who are chronically infected with the hepatitis C virus (HCV) remains an unmet medical need. METHODS: We conducted a phase 3, double-blind, placebo-controlled study involving untreated and previously treated patients with chronic HCV genotype 1, 2, 4, 5, or 6 infection, including those with compensated cirrhosis. Patients with...
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