Article
Sofosbuvir With Velpatasvir in Treatment-Naive Noncirrhotic Patients With Genotype 1 to 6 Hepatitis C Virus Infection: A Randomized Trial.
Annals of internal medicine - 1 Dec 2015
Everson Gregory T, Towner William J, Davis Mitchell N, Wyles David L, Nahass Ronald G, Thuluvath Paul J, Etzkorn Kyle, Hinestrosa Federico, Tong Myron, Rabinovitz Mordechai, McNally John, Brainard Diana M, Han Lingling, Doehle Brian, McHutchison John G, Morgan Timothy, Chung Raymond T, Tran Tram T
Abstract excerpt
BACKGROUND: Effective, pangenotypic treatments for hepatitis C virus (HCV) infection are needed. OBJECTIVE: To assess the safety and efficacy of sofosbuvir with velpatasvir in patients infected with HCV genotypes 1 to 6. DESIGN: Randomized, phase 2, open-label study. (ClinicalTrials.gov: NCT01858766). SETTING: 48 U.S. sites. PATIENTS: 377 treatment-naive noncirrhotic patients. In part A, patients infected with...
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