Article
Sofosbuvir and Velpatasvir for HCV in Patients with Decompensated Cirrhosis.
The New England journal of medicine - 31 Dec 2015
Curry Michael P, O'Leary Jacqueline G, Bzowej Natalie, Muir Andrew J, Korenblat Kevin M, Fenkel Jonathan M, Reddy K Rajender, Lawitz Eric, Flamm Steven L, Schiano Thomas, Teperman Lewis, Fontana Robert, Schiff Eugene, Fried Michael, Doehle Brian, An Di, McNally John, Osinusi Anu, Brainard Diana M, McHutchison John G, Brown Robert S, Charlton Michael
Abstract excerpt
BACKGROUND: As the population that is infected with the hepatitis C virus (HCV) ages, the number of patients with decompensated cirrhosis is expected to increase. METHODS: We conducted a phase 3, open-label study involving both previously treated and previously untreated patients infected with HCV genotypes 1 through 6 who had decompensated cirrhosis (classified as Child-Pugh-Turcotte class B). Patients were...
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