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Article

Molding BRCA2 function through its interacting partners.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Martinez Juan S, Baldeyron Céline, Carreira Aura

Abstract excerpt

The role of the tumor suppressor BRCA2 has been shaped over 2 decades thanks to the discovery of its protein and nucleic acid partners, biochemical and structural studies of the protein, and the functional evaluation of germline variants identified in breast cancer patients. Yet, the pathogenic and functional effect of many germline mutations in BRCA2 remains undetermined, and the heterogeneity of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26566862
DOI: 10.1080/15384101.2015.1093702
PMCID: PMC4825613

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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