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Outlier DNA methylation levels as an indicator of environmental exposure and risk of undesirable birth outcome

12 Nov 2015

Abstract excerpt

We have identified a novel molecular phenotype that defines a subgroup of newborns who have highly disrupted epigenomes. We profiled DNA methylation in cord blood of 114 children selected from the lowest and highest quintiles of the birth weight distribution (irrespective of their mode of conception) at 96 CpG sites in genes we have found previously to be related to birth weight or growth and metabolism. We...

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Share to Epigenetics and DNA Methylation
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PMID: 26566672
DOI: 10.1093/hmg/ddv458

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