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Birthweight, Maternal Weight Trajectories and Global DNA Methylation of LINE-1 Repetitive Elements

28 Sept 2011

Abstract excerpt

Low birthweight, premature birth, intrauterine growth retardation, and maternal malnutrition have been related to an increased risk of cardiovascular disease, type 2 diabetes mellitus, obesity, and neuropsychiatric disorders later in life. Conversely, high birthweight has been linked to future risk of cancer. Global DNA methylation estimated by the methylation of repetitive sequences in the genome is an indicator...

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PMID: 21980406
DOI: 10.1371/journal.pone.0025254

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