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Article

Detection of genetic purging and predictive value of purging parameters estimated in pedigreed populations.

Heredity - 1 Jul 2018

López-Cortegano Eugenio, Bersabé Diego, Wang Jinliang, García-Dorado Aurora

Abstract excerpt

The consequences of inbreeding for fitness are important in evolutionary and conservation biology, but can critically depend on genetic purging. However, estimating purging has proven elusive. Using PURGd software, we assess the performance of the Inbreeding-Purging (IP) model and of ancestral inbreeding (Fa) models to detect purging in simulated pedigreed populations, and to estimate parameters that allow...

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Identifiers

PMID: 29434337
DOI: 10.1038/s41437-017-0045-y
PMCID: PMC5997712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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