Article
Mannan-binding lectin at supraphysiological concentrations inhibits differentiation of dendritic cells from human CD14+ monocytes.
Microbiology and immunology - 1 Dec 2015
Xu Xiao-Ying, Li Hui-Jie, Zhang Li-Yun, Lu Xiao, Zuo Da-Ming, Shan Gui-Qiu, Xu Tian-Yu, Chen Zheng-Liang
Abstract excerpt
Mannan-binding lectin (MBL), a circulating C-type lectin, is an important member of the defense collagen family. It exhibits a high potential for recognizing broad categories of pathogen-associated molecular patterns and initiating complement cascade responses. DCs are well-known specialist antigen-presenting cells that significantly trigger specific T cell-mediated immune responses. In our previous study, it was...
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