Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Performance of Droplet Digital PCR in Non-Invasive Fetal RHD Genotyping - Comparison with a Routine Real-Time PCR Based Approach.

PloS one - 1 Jan 2015

Svobodová Iveta, Pazourková Eva, Hořínek Aleš, Novotná Michaela, Calda Pavel, Korabečná Marie

Abstract excerpt

Detection and characterization of circulating cell-free fetal DNA (cffDNA) from maternal circulation requires an extremely sensitive and precise method due to very low cffDNA concentration. In our study, droplet digital PCR (ddPCR) was implemented for fetal RHD genotyping from maternal plasma to compare this new quantification alternative with real-time PCR (qPCR) as a golden standard for quantitative analysis of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Specimen Collection
Share to Fetus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotyping Techniques

Share to Gestational Age

Share to Prenatal Diagnosis

Share to Real-Time Polymerase Chain Reaction

Share to Reproducibility of Results

Share to Rh-Hr Blood-Group System

Source

Open in PubMed Open full text

Identifiers

PMID: 26562517
DOI: 10.1371/journal.pone.0142572
PMCID: PMC4642940

Genes

RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Performance of Droplet Digital PCR in Non-Invasive Fetal RHD Genotyping - Comparison with a Routine Real-Time PCR Based Approach.PMID 26562517Read ↗

Droplet digital PCR, a new approach to analyze fetal DNA from maternal blood: application to the determination of fetal RHD genotype.Semantic proximity Read ↗

Optimized Droplet Digital PCR Assay on Cell-Free DNA Samples for Non-Invasive Prenatal Diagnosis: Application to Beta-Thalassemia.Semantic proximity Read ↗

[Development of digital PCR molecular tests for clinical practice: principles, practical implementation and recommendations].Semantic proximity Read ↗

Droplet‑based digital PCR for non‑invasive prenatal genetic diagnosis of α and β‑thalassemiaSemantic proximity Read ↗

Droplet Digital PCR for Non-Invasive Prenatal Detection of Fetal Single-Gene Point Mutations in Maternal Plasma.Semantic proximity Read ↗

Nonivasive prenatal diagnosis of single-gene disorders using droplet digital PCRSemantic proximity Read ↗

A multiplex droplet digital PCR assay for non-invasive prenatal testing of fetal aneuploidiesSemantic proximity Read ↗

Digital PCR and its applications in noninvasive prenatal testingSemantic proximity Read ↗

Application of Digital Polymerase Chain Reaction (dPCR) in Non-Invasive Prenatal Testing (NIPT)Semantic proximity Read ↗

Standardization non-invasive fetal RHD and SRY determination into clinical routine using a new multiplex RT-PCR assay for fetal cell-free DNA in pregnant women plasma: Results in clinical benefits and cost savingSemantic proximity Read ↗

Fetal Sex and RHD Genotyping with Digital PCR Demonstrates Greater Sensitivity than Real-time PCR.Semantic proximity Read ↗

Preanalytical blood sample workup for cell-free DNA analysis using Droplet Digital PCR for future molecular cancer diagnostics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.