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Droplet digital PCR, a new approach to analyze fetal DNA from maternal blood: application to the determination of fetal RHD genotype.

Annales de biologie clinique - 1 Jun 2016

Orhant Lucie, Rondeau Sophie, Vasson Aurélie, Anselem Olivia, Goffinet François, Allach El Khattabi Laïla, Leturcq France, Vidaud Dominique, Bienvenu Thierry, Tsatsaris Vassilis, Nectoux Juliette

Abstract excerpt

The discovery of free fetal DNA in the maternal circulation has inaugurated the era of non-invasive prenatal diagnosis. The latter has the advantage of avoiding the use of conventional obstetric procedures, such as chorionic villus sampling or aspiration of amniotic fluid, thus limiting the risks of miscarriage they induce. However, as free fetal DNA accounts for about 10% of cell-free DNA in maternal plasma, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27237800
DOI: 10.1684/abc.2016.1139

Genes

RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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