Article
Integrative phenotyping framework (iPF): integrative clustering of multiple omics data identifies novel lung disease subphenotypes.
BMC genomics - 11 Nov 2015
Kim SungHwan, Herazo-Maya Jose D, Kang Dongwan D, Juan-Guardela Brenda M, Tedrow John, Martinez Fernando J, Sciurba Frank C, Tseng George C, Kaminski Naftali
Abstract excerpt
BACKGROUND: The increased multi-omics information on carefully phenotyped patients in studies of complex diseases requires novel methods for data integration. Unlike continuous intensity measurements from most omics data sets, phenome data contain clinical variables that are binary, ordinal and categorical. RESULTS: In this paper we introduce an integrative phenotyping framework (iPF) for disease subtype...
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