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AutoFocus: A hierarchical framework to explore multi-omic disease associations spanning multiple scales of biomolecular interaction

2023-09-07

Abstract excerpt

Recent advances in high-throughput measurement technologies have enabled the analysis of molecular perturbations associated with disease phenotypes at the multi-omic level. Such perturbations can range in scale from fluctuations of individual molecules to entire biological pathways. Data-driven clustering algorithms have long been used to group interactions into interpretable functional modules; however, these mod...

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Literature Corpus work
63723a0d-f2cf-51d5-b8bf-6512ded2aa17
DOI
10.1101/2023.09.06.556542
Open publication

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AutoFocus: A hierarchical framework to explore multi-omic disease associations spanning multiple scales of biomolecular interactionDOI 10.1101/2023.09.06.556542
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