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Article

Differences in sleep disturbances among offspring of parents with and without bipolar disorder: association with conversion to bipolar disorder.

Bipolar disorders - 1 Dec 2015

Levenson Jessica C, Axelson David A, Merranko John, Angulo Melina, Goldstein Tina R, Mullin Benjamin C, Goldstein Benjamin I, Brent David A, Diler Rasim, Hickey Mary Beth, Monk Kelly, Sakolsky Dara, Kupfer David J, Birmaher Boris

Abstract excerpt

OBJECTIVES: Disruptions in sleep and dysregulation in circadian functioning may represent core abnormalities in the pathophysiology of bipolar disorder (BP). However, it is not clear whether these dysfunctions are state or trait markers of BP. This report compared sleep and circadian phenotypes among three groups: offspring of parents with BP diagnosed with BP at intake (BP/OB; n = 47), offspring of parents with...

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Identifiers

PMID: 26547512
DOI: 10.1111/bdi.12345
PMCID: PMC4734929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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