Article
Controlled, blindly rated, direct-interview family study of a prepubertal and early-adolescent bipolar I disorder phenotype: morbid risk, age at onset, and comorbidity.
Archives of general psychiatry - 1 Oct 2006
Geller Barbara, Tillman Rebecca, Bolhofner Kristine, Zimerman Betsy, Strauss Nancy A, Kaufmann Patricia
Abstract excerpt
CONTEXT: A key question is whether a prepubertal and early-adolescent bipolar I disorder phenotype (PEA-BP-I) is the same illness as adult BP-I. This question arises because of the greater severity, longer current episode duration, preponderance of mania, and high rates of ultradian rapid cycling and comorbid attention-deficit/hyperactivity disorder (ADHD) in PEA-BP-I. OBJECTIVES: To examine morbid risk (MR) of...
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