Article
Early stages in the development of bipolar disorder.
Journal of affective disorders - 1 Feb 2010
Duffy Anne, Alda Martin, Hajek Tomas, Sherry Simon B, Grof Paul
Abstract excerpt
BACKGROUND: Numerous studies have observed that offspring of bipolar parents manifest a broad spectrum of psychiatric disorders. We tested the hypothesis that in high risk offspring, bipolar disorder evolves in a predictable clinical sequence from non-specific (non-mood) to specific (mood) psychopathology. METHODS: Offspring from well-characterized families with one bipolar parent (high risk) or two well parents...
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