Article
Correlation between the germline methylation status in ERβ promoter and the risk in prostate cancer: a prospective study.
Familial cancer - 1 Apr 2016
Wang Lihui, Zhang Pan, Meng Xiannan, Chen Xiang, Xiang Zou, Lin Xiaoqian, Liu Ye, Gan Weidong, Han Xiaodong, Li Dongmei
Abstract excerpt
Familial aggregation of cancer may reflect an overall contribution of inherited genes or a shared mechanism for the manipulation of gene function. DNA methylation in the promoter regions is considered to be a mechanism through which tumor suppressor genes are inhibited, which will lead to tumorigenesis and tumor progression. To evaluate the association between the methylation status in the promoter of estrogen...
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