Article
Up-Regulation of S100A11 in Lung Adenocarcinoma - Its Potential Relationship with Cancer Progression.
PloS one - 1 Jan 2015
Woo Tetsukan, Okudela Koji, Mitsui Hideaki, Tajiri Michihiko, Rino Yasushi, Ohashi Kenichi, Masuda Munetaka
Abstract excerpt
We previously reported that patients with lung adenocarcinomas with KRAS gene mutations and strong proliferating activity had poorer outcomes, even in the early stage of the disease. The aim of the present study was to elucidate the potential molecular basis of these highly malignant lung tumors by focusing on S100 proteins (S100A2, S100A7, and S100A11), which are downstream targets of oncogenic KRAS and...
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