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Histone acetylation: novel target for the treatment of acute lymphoblastic leukemia

4 Nov 2015

Abstract excerpt

Acute lymphoblastic leukemia (ALL) has been generally considered a genetic disease (disorder) with an aggressive tumor entity of highly proliferative malignant lymphoid cells. However, in recent years, significant advances have been made in the elucidation of the ALL-associated processes. Thus, we understand that histone acetylation is involved in the permanent changes of gene expression controlling ALL...

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Share to Acute Lymphoblastic Leukemia research
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PMID: 26543507
DOI: 10.1186/s13148-015-0151-8

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