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Aberrant DNA methylation of key genes and Acute Lymphoblastic Leukemia

20 Nov 2017

Abstract excerpt

DNA methylation is a dynamic process influencing gene expression by altering either coding or non-coding loci. Despite advances in treatment of Acute Lymphoblastic Leukemia (ALL); relapse occurs in approximately 20% of patients. Nowadays, epigenetic factors are considered as one of the most effective mechanisms in pathogenesis of malignancies. These factors are reversible elements which can be potentially...

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PMID: 29793312
DOI: 10.1016/j.biopha.2017.11.033

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