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Article

Activating KIRs alter susceptibility to pulmonary tuberculosis in a South African population.

Tuberculosis (Edinburgh, Scotland) - 1 Dec 2015

Salie Muneeb, Daya Michelle, Möller Marlo, Hoal Eileen G

Abstract excerpt

We investigate the role of killer immunoglobulin-like receptor (KIR) genes and human leukocyte antigen class-I (HLA) variants in susceptibility to tuberculosis in a South African population. In a sample set comprising 408 TB cases and 351 healthy controls, we show that the KIR3DS1 gene and KIR genotypes with five or more activating KIRs, and the presence of 3DS1, protect against developing active TB in the South...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26542219
DOI: 10.1016/j.tube.2015.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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