Article
Breast Cancer beyond the Age of Mutation.
Gerontology - 1 Jan 2016
LaBarge Mark A, Mora-Blanco E Lorena, Samson Susan, Miyano Masaru
Abstract excerpt
Age is the greatest risk factor for breast cancer, but the reasons underlying this association are unclear. While there is undeniably a genetic component to all cancers, the accumulation of mutations with age is insufficient to explain the age-dependent increase in breast cancer incidence. In this viewpoint, we propose a multilevel framework to better understand the respective roles played by somatic mutation,...
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