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Article

A real-time PCR assay for direct characterization of the Neisseria gonorrhoeae GyrA 91 locus associated with ciprofloxacin susceptibility.

The Journal of antimicrobial chemotherapy - 1 Feb 2016

Buckley Cameron, Trembizki Ella, Donovan Basil, Chen Marcus, Freeman Kevin, Guy Rebecca, Kundu Ratan, Lahra Monica M, Regan David G, Smith Helen, Whiley David M

Abstract excerpt

OBJECTIVES: The objective of this study was to develop a real-time PCR method for specific detection of the gonococcal GyrA amino acid 91 locus directly in clinical samples so as to predict Neisseria gonorrhoeae ciprofloxacin susceptibility. METHODS: The real-time PCR assay, GyrA91-PCR, was designed using two probes, one for detection of the WT S91 sequence and the other for detection of the S91F alteration. The...

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Identifiers

PMID: 26538505
DOI: 10.1093/jac/dkv366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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