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Predominant role of msr(D) over mef(A) in macrolide resistance in Streptococcus pyogenes

2 Nov 2015

Abstract excerpt

In Japan, the number of patients with streptococcal toxic shock syndrome is reported to be increasing. mef(A) gene-positive macrolide-resistant emm1 strains are thought to possibly contribute to the rise in the frequency of STSS. Although analyses of macrolide-resistant mechanisms, including mef(A) resistance, have been performed mainly in Streptococcus pneumoniae, the role of this gene in Streptococcus pyogenes...

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PMID: 26531240
DOI: 10.1099/mic.0.000206

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