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Article

Single nucleotide polymorphisms in 5'-UTR of the SLC2A4 gene regulate solute carrier family 2 member 4 gene expression in visceral adipose tissue.

Gene - 15 Jan 2016

Malodobra-Mazur Malgorzata, Bednarska-Chabowska Dorota, Olewinski Robert, Chmielecki Zygmunt, Adamiec Rajmund, Dobosz Tadeusz

Abstract excerpt

BACKGROUND: The glucose uptake by numerous cells like adipocytes or skeletal muscle cells requires activation of specific proteins called glucose transporters. GLUT4 content and its activation as well as SLC2A4 gene expression level are decreased in patients with type 2 diabetes. The SLC2A4 gene expression rate might be modulated by genetic variances in UTRs. The relationship between two SNPs in 5'UTR and one SNP...

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Identifiers

PMID: 26529385
DOI: 10.1016/j.gene.2015.10.067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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