Article
Polymorphisms in the presumptive promoter region of the SLC2A9 gene are associated with gout in a Chinese male population.
PloS one - 1 Jan 2012
Li Changgui, Chu Nan, Wang Binbin, Wang Jing, Luan Jian, Han Lin, Meng Dongmei, Wang Yunlong, Suo Peisu, Cheng Longfei, Ma Xu, Miao Zhimin, Liu Shiguo
Abstract excerpt
BACKGROUND: Glucose transporter 9 (GLUT9) is a high-capacity/low-affinity urate transporter. To date, several recent genome-wide association studies (GWAS) and follow-up studies have identified genetic variants of SLC2A9 associated with urate concentrations and susceptibility to gout. We therefor...
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