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Cerebellar activity in young people with familial risk for psychosis--The Oulu Brain and Mind Study.

Schizophrenia research - 1 Dec 2015

Jukuri Tuomas, Kiviniemi Vesa, Nikkinen Juha, Miettunen Jouko, Mäki Pirjo, Mukkala Sari, Koivukangas Jenni, Nordström Tanja, Moilanen Irma, Barnett Jennifer H, Jones Peter B, Murray Graham K, Veijola Juha

Abstract excerpt

OBJECTIVE: The cerebellum plays a critical role in cognition and behavior. Altered function of the cerebellum has been related to schizophrenia and psychosis but it is not known how this applies to spontaneous resting state activity in young people with familial risk for psychosis. METHODS: We conducted resting-state functional MRI (R-fMRI) in 72 (29 male) young adults with a history of psychosis in one or both...

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PMID: 26527249
DOI: 10.1016/j.schres.2015.10.010

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