Article
Medial temporal lobe default mode functioning and hippocampal structure as vulnerability indicators for schizophrenia: a MRI study of non-psychotic adolescent first-degree relatives.
Schizophrenia research - 1 Nov 2014
Seidman Larry J, Rosso Isabelle M, Thermenos Heidi W, Makris Nikos, Juelich Richard, Gabrieli John D E, Faraone Stephen V, Tsuang Ming T, Whitfield-Gabrieli Susan
Abstract excerpt
BACKGROUND: Clues to the etiology and pathophysiology of schizophrenia can be examined in their first-degree relatives because they are genetically related to an ill family member, and have few confounds like medications. Brain abnormalities observed in young relatives are neurobiological indicators of vulnerability to illness. We examined the hypothesis that the hippocampus and parahippocampus are structurally...
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